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Related Experiment Video

Updated: Dec 29, 2025

Author Spotlight: Developing a Rat Model for Weight-Bearing Intervention to Investigate Osteonecrosis of the Femoral Head

Author Spotlight: Developing a Rat Model for Weight-Bearing Intervention to Investigate Osteonecrosis of the Femoral Head

Published on: September 27, 2024

[Multiple osteonecrosis. Update and case report].

V Gallart Úbeda¹, J M Elía Martínez¹, R Puerta de Diego¹

¹Servicio de Medicina Física y Rehabilitación, Consorcio Hospital General Universitario de Valencia, Valencia, España.

|February 3, 2020

Summary

This summary is machine-generated.

Multifocal osteonecrosis, affecting three or more bone sites, is rare. This case highlights risk factors like abnormal hemostasis and medication history in developing this condition.

Keywords:

Coagulation disorders Corticosteroids Glucocorticoides Multiple osteonecrosis Osteonecrosis múltiple Trastornos de la coagulación Tratamiento Treatment

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Last Updated: Dec 29, 2025

Author Spotlight: Developing a Rat Model for Weight-Bearing Intervention to Investigate Osteonecrosis of the Femoral Head

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Published on: March 14, 2019

Area of Science:

Orthopedics
Rheumatology
Hematology

Background:

Multifocal osteonecrosis (MFON) is rare, affecting <3% of osteonecrosis patients.
Associated with systemic diseases: lupus, transplant recipients, hematologic disorders, and high-dose glucocorticoids.
Femoral head is the most commonly affected site.

Observation:

A young woman presented with bilateral hip osteonecrosis.
She had abnormal hemostatic factors and a history of glucocorticoid and oral contraceptive use.
Subsequently developed shoulder osteonecrosis.

Findings:

Presents a case of multifocal osteonecrosis in a young woman.
Highlights potential contributing factors including hemostatic abnormalities and specific therapies.
Reviews the etiology and treatment of multifocal osteonecrosis.

Implications:

Underscores the importance of considering multifocal osteonecrosis in patients with specific risk factors.
Suggests a need for further research into the pathogenesis of MFON.
Informs clinical evaluation and management strategies for patients at risk.