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Updated: Dec 29, 2025

Author Spotlight: Advancing Biomedical Research Through Single Cell Analysis
Published on: December 22, 2023
Single-cell biomedicine: roles of single-cell nuclear elements
Yiming Zeng1, Xiangdong Wang2, Jiaqiang Zhang3
1Department of Pulmonary and Critical Care Medicine, Clinical Center for Molecular Diagnosis and Therapy, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian Province, China. zeng_yi_ming@126.com.
Abstract:
Single-cell biomedicine, a new merging discipline of cell biology and medicine to improve the life quality of patients, gains high priority in cell biology and toxicology. Single-cell nuclear elements are specially focused and headlined to understand regulatory mechanisms by which transcriptional factors, DNA elements, and genome organization interact with each other and contribute to the developmental evolution and dynamic formation of genotoxicity. Cell molecular phenomics, clonal genotypes, and structural metamorphoses during the cell cycle at single-cell level provide deep insights to understanding mechanism-based bridges between cell biology and toxicology, between cell sensitive and resistance, and between chronic diseases and cancer.
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