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Updated: Dec 29, 2025

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
Collaborative Antimicrobial Stewardship in the Emergency Department.
Nicole M Acquisto1, Larissa May2
1Department of Pharmacy, University of Rochester Medical Center, 601 Elmwood Avenue, Box 638, Rochester, NY 14642, USA; Department of Emergency Medicine, University of Rochester Medical Center, 601 Elmwood Avenue, Box 655, Rochester, NY 14642, USA.
Antimicrobial stewardship (AS) in the emergency department (ED) is crucial for reducing antibiotic overuse. This article outlines key ED-focused AS strategies and collaborations to improve patient care and prevent readmissions.
Area of Science:
- Infectious Diseases
- Public Health
- Health Services Research
Background:
- Emergency departments (EDs) manage a high patient volume, contributing to antibiotic overprescribing concerns.
- The ED's unique position necessitates collaboration across healthcare settings for effective antimicrobial stewardship (AS).
Purpose of the Study:
- To detail effective ED-focused antimicrobial stewardship (AS) strategies.
- To highlight the importance of inter-professional collaboration for successful AS initiatives in the ED.
Main Methods:
- Review of current ED-focused AS strategies.
- Discussion of collaborative models between ED AS leadership and healthcare partners.
- Exploration of future expansion possibilities for ED AS programs.
Main Results:
- EDs are pivotal settings for implementing antimicrobial stewardship (AS) to combat antibiotic resistance.
- Effective AS in the ED requires strategic approaches to antimicrobial selection and administration.
- Collaboration is key to preventing ED return visits and hospital readmissions.
Conclusions:
- Targeted antimicrobial stewardship (AS) initiatives in the emergency department (ED) are essential for optimizing antibiotic use.
- Successful ED AS programs require strong collaboration with inpatient, ambulatory, and long-term care facilities.
- Future strategies should focus on expanding ED AS to further enhance patient outcomes and combat antimicrobial resistance.
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