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Stable multi-megahertz circular-ranging optical coherence tomography at 1.3 µm.

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This study introduces a new circular-ranging optical coherence tomography (CR-OCT) system that overcomes previous stability and wavelength limitations. The enhanced CR-OCT design enables deeper imaging in tissues and broader applications in medicine and beyond.

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Area of Science:

  • Biomedical Engineering
  • Optical Physics
  • Medical Imaging

Background:

  • Fourier-domain optical coherence tomography (OCT) systems face depth and speed limitations due to finite electronic bandwidth.
  • Existing circular-ranging OCT (CR-OCT) methods offer improved range but suffer from instability and operate at suboptimal wavelengths (1.55 µm).

Purpose of the Study:

  • To develop a novel CR-OCT architecture that enhances stability, simplifies design, and shifts the operating wavelength for improved biological tissue penetration.
  • To overcome the limitations of previous CR-OCT systems, enabling wider applicability.

Main Methods:

  • Replaced temperature-sensitive optical modules and eliminated long fiber spools in favor of a 10-meter chirped fiber Bragg grating (CFBG).
  • Implemented an active quadrature demodulation circuit using a lithium niobate phase modulator.
  • Shifted the operating wavelength to 1.29 µm using CFBG-based dispersive fibers for enhanced tissue imaging.

Main Results:

  • Achieved a stable CR-OCT system with a simplified design.
  • Demonstrated operation at 1.29 µm, improving imaging penetration.
  • Maintained a broad 100 nm optical bandwidth, a 4 cm imaging range, and a high 7.6 MHz A-line rate.

Conclusions:

  • The novel CR-OCT architecture significantly enhances stability and simplifies system design compared to previous methods.
  • Operating at 1.29 µm allows for deeper imaging in biological tissues.
  • This improved CR-OCT system is poised for broader exploration in medical and non-medical fields.