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Updated: Dec 29, 2025

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
Transversal dose profile reconstruction for clinical proton beams: A detectors inter-comparison
R Catalano1, G Petringa1, G Cuttone1
1INFN-LNS, Istituto Nazionale di Fisica Nucleare - Laboratori Nazionali del Sud, Via S. Sofia, 62, 95123 Catania, Italy.
A new beam profiling system shows promise for proton therapy quality assurance. This system, using a scintillator and CCD detector, accurately reconstructs transversal dose profiles, aligning well with established methods like radiochromic films.
Area of Science:
- Medical Physics
- Radiation Oncology
- Nuclear Instrumentation
Background:
- Proton therapy requires precise daily quality assurance (QA) for accurate dose delivery.
- Transversal dose profile reconstruction is crucial for verifying beam characteristics.
- Existing QA methods, such as radiochromic films, serve as established references.
Purpose of the Study:
- To inter-compare different devices for transversal dose profile reconstruction in proton therapy.
- To evaluate a novel beam profiling system developed at INFN-LNS for daily QA.
Main Methods:
- Comparison of EBT3 radiochromic films (reference) with other QA devices.
- Utilized a newly developed beam profiling system: a 1mm plastic scintillator screen with a CCD detector.
- Tests conducted at INFN-LNS and Trento Proton Therapy Center facilities.
Main Results:
- General good agreement observed between the tested detectors.
- The INFN-LNS beam profiling system demonstrated a linear response within the relevant dose rate range for proton therapy.
- The system offers high spatial resolution and efficient acquisition/processing times.
Conclusions:
- The developed beam profiling system is a promising tool for 2-D relative dosimetry in proton therapy QA.
- Its performance characteristics support its potential for routine clinical use.
- The system provides a viable alternative for accurate and efficient beam profile verification.
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