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Efficient photosensitizers with aggregation-induced emission characteristics for lysosome- and Gram-positive
Jiabao Zhuang1, Hanxiao Yang1, Yue Li1
1Key Laboratory of Macromolecular Science of Shaanxi Province, Key Laboratory of the Ministry of Education for Medicinal Resources and Natural Pharmaceutical Chemistry, School of Chemistry & Chemical Engineering, Shaanxi Normal University, 710119 Xi'an, China. nli@snnu.edu.cn nzhao@snnu.edu.cn.
Abstract:
Two efficient photosensitizers (PSs) with aggregation-induced emission characteristics were designed and synthesized for specific lysosome-targeted photodynamic therapy (PDT). Both PSs efficiently discriminated Gram-positive bacteria from Gram-negative bacteria and killed Gram-positive bacteria through the PDT effect.
