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Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models
08:32

Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models

Published on: March 1, 2015

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Airway protection & patterns of dysphagia in infants with down syndrome: Videofluoroscopic swallow study findings &

Amit Narawane1, James Eng2, Christina Rappazzo3

  • 1Baylor College of Medicine, USA.

International Journal of Pediatric Otorhinolaryngology
|February 5, 2020
PubMed

Insights

Infants with Down syndrome frequently experience oral and pharyngeal dysphagia, impacting airway protection. Early swallowing assessments are crucial, particularly for those with respiratory issues.

Area of Science:

  • Pediatric Medicine
  • Genetics
  • Speech-Language Pathology

Background:

  • Down syndrome is a common genetic condition affecting approximately 1 in 737 births.
  • Infants with Down syndrome often present with cardiac, otolaryngologic, and developmental anomalies.
  • Swallowing difficulties (dysphagia) are common in infants with Down syndrome, potentially leading to respiratory infections.

Purpose of the Study:

  • To characterize the nature of airway protection and dysphagia in infants diagnosed with Down syndrome.
  • To identify specific patterns of oral and pharyngeal phase swallowing impairments.

Main Methods:

  • A retrospective chart review was conducted on infants with Down syndrome.
  • Data were collected from videofluoroscopic swallow studies (VFSS) performed between 2008 and 2018.
  • Demographic information and VFSS findings related to swallowing function were analyzed.

Main Results:

  • A high prevalence of oral dysphagia (89.8%) and pharyngeal dysphagia (72.4%) was observed.
  • Abnormalities in sucking skills (63.7%) and bolus formation/control (62.2%) were frequent.
  • Impaired swallow initiation (53.5%), presence of oral residuals (37.8%), pharyngeal residue (17.3%), and pharyngo-nasal reflux (27.5%) were noted.

Conclusions:

  • Swallowing assessments are recommended for infants with Down syndrome, especially those with suspected dysphagia.
  • Particular attention should be given to infants with Down syndrome experiencing pulmonary health alterations.
  • Early identification and intervention for dysphagia can mitigate risks associated with respiratory complications.
Abstract

Keywords:
Down syndromeFeeding difficultyInfant dysphagiaInfant swallowingPediatric dysphagiaSwallowing difficultyTracheal aspiration in infantsTrisomy 21Videofluoroscopic swallow study

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