Hirsutism Induced by Facial Autologous Fat Grafting

Autologous fat grafting (AFG) is a common procedure, which gains popularity for a large number of indications, mainly for reshaping and filling of contour defects. It is considered a safe procedure, with only uncommon and mild complications. Here we report on a 60-year-old female patient who developed excess hair growth on both cheeks 1 month following facial AFG done in conjunction with a facelift. Complete endocrine evaluation was within normal levels. Previous reports have suggested that adipocyte mesenchymal stem cells can secrete a number of growth factors, which in turn can lead to activation of stem cells in the hair follicle, affecting their growth. However, to the best of our knowledge, this is the first report on hirsutism as a side effect of AFG.