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Author Spotlight: Developing Parmodulins to Target Protease-Activated Receptors for Inflammation Control
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Author Spotlight: Developing Parmodulins to Target Protease-Activated Receptors for Inflammation Control

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Lead Optimization and Avoidance of Reactive Metabolite Leading to PCO371, a Potent, Selective, and Orally Available

Yoshikazu Nishimura1, Toru Esaki1, Yoshiaki Isshiki1

  • 1Research Division, Chugai Pharmaceutical Co., Ltd., Komakado 1-135, Gotemba, Shizuoka 412-8513, Japan.

Journal of Medicinal Chemistry
|February 6, 2020
PubMed

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