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Brain Imaging

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...

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Related Experiment Video

Updated: Dec 29, 2025

Author Spotlight: Advancing Pediatric Epilepsy Surgery in Children Through Novel Biomarkers and Enhanced Localization

Author Spotlight: Advancing Pediatric Epilepsy Surgery in Children Through Novel Biomarkers and Enhanced Localization

Published on: September 20, 2024

Advanced neuroimaging techniques for evaluating pediatric epilepsy.

Yun Jeong Lee¹

¹Department of Pediatrics, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, Daegu, Korea.

Clinical and Experimental Pediatrics

|February 7, 2020

Summary

Advanced neuroimaging techniques improve the noninvasive identification of the seizure onset zone in epilepsy. These methods aid in surgical planning to enhance outcomes and prevent neurological deficits.

Keywords:

Child Diffusion tensor imaging Epilepsy Functional magnetic resonance imaging Neuroimaging

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Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy

Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy

Published on: December 6, 2016

Area of Science:

Neurology
Radiology
Medical Imaging

Background:

Accurate localization of the seizure onset zone is critical for successful epilepsy surgery.
Neuroimaging advances enhance the understanding and noninvasive identification of the seizure onset zone.
Experienced interpretation of epilepsy-specific MRI protocols improves seizure onset zone detection.

Purpose of the Study:

To review advanced neuroimaging modalities for localizing the seizure onset zone in epilepsy.
To highlight the role of these techniques in surgical planning and predicting outcomes.
To discuss methods for preventing neurological deficits post-surgery.

Main Methods:

Structural MRI with epilepsy-specific protocols.
Ultra-high-field imaging and machine learning for subtle abnormality detection.
Diffusion tensor imaging (tractography) for white matter mapping.
Arterial spin-labeling perfusion MRI, simultaneous EEG-fMRI, and MEG.
Integration with PET, SPECT, and intracranial EEG.

Main Results:

Advanced MRI detects subtle abnormalities in MRI-negative patients.
Tractography delineates white matter tracts to prevent deficits.
Functional imaging (MEG, fMRI) localizes critical brain functions (language, motor, memory).
Combined modalities improve understanding of epileptic networks.
Valuable clinical information for predicting long-term outcomes in pediatric epilepsy.

Conclusions:

Advanced structural and functional neuroimaging are crucial for precise seizure onset zone localization.
These techniques aid in surgical planning, reducing neurological impairment risks.
Multimodal imaging approaches enhance the understanding of epilepsy networks and long-term outcomes.