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Updated: Dec 29, 2025

Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses

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Published on: June 13, 2018

Calciphylaxis: A Deceiving Cellulitis.

Sreenath Meegada¹, Madhavi Annakula¹, Tejo Challa¹

¹Internal Medicine, The University of Texas Health Science Center/Christus Good Shepherd Medical Center, Longview, USA.

|February 7, 2020

Summary

This summary is machine-generated.

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Calciphylaxis, a rare condition in dialysis patients, involves calcium deposits in skin blood vessels, causing painful lesions. Early recognition is crucial for appropriate treatment of this serious disorder.

Area of Science:

Nephrology
Dermatology
Vascular Biology

Background:

Calciphylaxis is a rare, severe condition predominantly affecting end-stage renal disease (ESRD) patients undergoing dialysis.
It is characterized by calcification of small and medium-sized blood vessels in the skin and subcutaneous fat.

Observation:

Patients present with painful skin lesions, including plaques, ulcerations, and gangrene.
These lesions can lead to secondary infections, increasing morbidity and mortality.

Findings:

The underlying mechanism involves calcium deposition in dermal and subcutaneous vasculature.
This vascular compromise results in tissue ischemia and necrosis.

Implications:

Increased awareness among healthcare providers is essential for timely diagnosis.

Keywords:

calciphylaxis cellulitis end stage renal disease

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Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses

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Considering calciphylaxis in the differential diagnosis of cellulitis in at-risk patients can improve patient outcomes.

Further research into the pathogenesis and treatment of calciphylaxis is warranted.