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Radiosurgery for Symptomatic Cavernous Malformation in the Brainstem: Two Difficult Cases with Large and Multiple
1Neurological Surgery, Ookuma Hospital, Nagoya, JPN.
Cureus
|February 7, 2020
Summary
Cavernous malformations in the brainstem are dangerous and difficult to treat. Radiosurgery offers a viable treatment option for these complex cases after multiple hemorrhages.
Area of Science:
- Neurosurgery
- Neurology
- Radiology
Background:
- Cavernous malformations (CMs) can cause severe neurological deficits, especially in the brainstem.
- Brainstem CMs carry a higher risk of hemorrhage and are challenging to manage surgically.
Observation:
- Two patients with symptomatic, recurrent brainstem hemorrhages from cavernous malformations were identified.
- One case involved a large, solitary lesion, while the other presented with multiple, familial lesions.
Findings:
- Microsurgery for these brainstem lesions was deemed too difficult and hazardous.
- Both patients were successfully treated with radiosurgery following repeated hemorrhages.
Implications:
- Radiosurgery presents a less invasive and effective alternative for managing complex brainstem cavernous malformations.
- This approach may improve outcomes for patients with otherwise intractable neurological symptoms due to brainstem CMs.

