Improving Post-Operative Outcomes in Aged and Diabetic Obese Mice
Keely Szilagyi1, Michael A Zieger2, Jiliang Li3
1Laboratory Animal Resource Center at the Indiana University School of Medicine, Indianapolis, IN.
Abstract:
Due to their small size, high metabolic rate, and large surface to volume ratio, mice are a challenge to work with surgically and pre-operatively. Working with mice that are more susceptible to anesthetic agents, aged, or obese (e.g., diabetic mice), provides even more challenges. In two separate studies, we found simple that supportive care measures during and after surgery improved post-operative outcomes.


