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[Significance of the stromal reaction in bladder cancer]
R Goertchen1, R Kluge, P Stosiek
1Institut für Pathologie, Bakteriologie und Serologie des Bezirkskrankenhauses Görlitz.
Archiv Fur Geschwulstforschung
|January 1, 1988
Abstract:
The stromal reaction (SR) is to be regarded as a cellular immunological defense reaction of the host organism against the tumor. Based on an analysis of inflammatory infiltrates in 60 bladder cancers the significance of SR was examined. An increase of the cellular reaction up to 1.0 cm tumor diameter and of the lymphocytes at the beginning of the cancer infiltration could be observed, but there exists no statistically evaluable correlation between SR and size, grading or infiltration of the cancer. From these findings it is suggested that stromal reaction in bladder cancer is unimportant for prognosis.