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Quantifying the Binding Interactions Between CuII and Peptide Residues in the Presence and Absence of Chromophores
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Copper(II) and Amylin Analogues: A Complicated Relationship

Mawadda Alghrably1, Dorota Dudek2, Abdul-Hamid Emwas3

  • 1Biological and Environmental Science and Engineering (BESE) , King Abdullah University of Science and Technology (KAUST) , 23955-6900 Thuwal , Saudi Arabia.

Inorganic Chemistry
|February 7, 2020
PubMed
Summary

Copper ions (Cu2+) interact with pramlintide and rat amylin, potentially impacting protein aggregation relevant to diseases. Cu2+ binding affects pramlintide aggregation but not rat amylin.

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