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Rare malignant ulcer related to primary intestinal diffuse large B-cell lymphoma: A case report
Ning Jia1, Yanping Tang1, Yang Li2
1Department of Gastroenterology, Tianjin Hospital of Integrated Traditional Chinese and Western Medicine.
Rationale:
The specific pathogenesis of the diffuse large B-cell lymphoma(DLBCL)is still indefinite and argumentative. It is known that DLBCL is the most common type of non-Hodgkin's lymphomas (NHL). A lot of cases of DLBCL such as primary gastric diffuse large B-cell lymphoma(PG-DLBCL) are reported. However, primary intestinal diffuse large B-cell lymphoma(PI-DLBCL) is unusual.
Patient Concerns:
We present a case of a 57-year-old male diagnosed in the Gastroenterology Department, which presented a bleeding duodenal ulcer with irregular borders.
Diagnoses:
The immunohistochemical staining showed: CD20(+++), CD10(+) and Ki-67>40%.
Interventions:
The patient was successfully treated by Poly-chemotherapy with R-CHOP (rituximab, cyclophosphamide, doxorubicin, vindesine and prednisolone).
Outcomes:
After 6 courses of chemotherapy treatment, the duodenal ulcer was completely healed by reviewing the UGIE.
Lessons:
Our report might give further strength to avoiding the erroneous and missed diagnosis for PI-DLBCL which is different from common duodenal ulcer.
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