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Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma
Published on: March 30, 2018
Huge Primary Cardiac Malignant Lymphoma in the Left Ventricle
Kazumasa Matsunaga1, Toshiro Kobayashi1, Masaya Takahashi1
1Department of Surgery, Saiseikai Yamaguchi General Hospital, Yamaguchi, Japan.
Abstract:
A 67-year-old man presented at the hospital with worsening exertional dyspnea. Echocardiography showed a tumor in the left ventricle (approximately 35 × 48 mm) that protruded into the left atrium and left ventricular outflow tract during systole. These findings suggested a high risk of sudden death resulting from aortic valve obstruction or tumor embolism. Surgical resection was performed. During the operation, the tumor was resected as completely as possible, together with part of the myocardium where it arose. Histopathologic examination showed diffuse large B-cell lymphoma. The patient received systemic chemotherapy and is alive after 1 year.
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