Related Experiment Video
Updated: Dec 29, 2025
14:39
Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
Published on: November 4, 2010
32.3K
Exercise-induced bronchoconstriction in elite or endurance athletes:: Pathogenesis and diagnostic considerations
Taylor J Atchley1, Derek M Smith1
1Wilford Hall Ambulatory Surgical Center, Lackland AFB, Texas.
Summary
Elite athletes may experience exercise-induced bronchoconstriction (EIB) due to environmental stressors. A diagnostic algorithm is proposed, emphasizing bronchoprovocative challenges over symptoms alone for accurate evaluation.
Area of Science:
- Sports Medicine
- Pulmonology
- Exercise Physiology
Background:
- Exercise-induced bronchoconstriction (EIB) is airway narrowing during exercise, affecting athletes with or without asthma.
- Environmental stressors like dry air, temperature changes, and pollutants contribute to EIB.
- Elite and endurance athletes face higher exposure to these stressors.
Purpose of the Study:
- To review the pathogenesis and evaluation of EIB in elite/endurance athletes.
- To propose a literature-based diagnostic algorithm for EIB in this population.
Main Methods:
- Literature search using Ovid MEDLINE and key article references.
- Inclusion of randomized controlled trials, systematic reviews, meta-analyses, and observational studies.
Main Results:
- EIB pathogenesis involves airway osmotic, thermal, and irritant responses during exercise.
- Elite athletes' prolonged exercise duration and intensity increase EIB risk.
- Symptoms alone are insufficient; objective testing is crucial.
Conclusions:
- Increased awareness and thorough evaluation of EIB in athletes are necessary.
- A diagnostic algorithm incorporating bronchoprovocative challenges is proposed.
- Further research is needed to validate predictive values of diagnostic tests.
Related Concept Videos
01:20Asthma: Pathogenesis and Management
1.1K
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
1.1K
01:20Chronic Obstructive Pulmonary Disease-II: Pathophysiology
4.1K
Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
Chronic Inflammation
4.1K
01:26Asthma-II: Pathophysiology and Classification
3.9K
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
3.9K
01:29Asthma-I: Introduction
3.3K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
3.3K
01:30Asthma-IV: Diagnostic and Management
3.0K
The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
3.0K
01:20Chronic Obstructive Pulmonary Disease-I: Introduction
3.4K
Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.
3.4K