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A patient-centered multidisciplinary cardiac rehabilitation program improves glycemic control and functional outcome

Andrea Denegri1, Valentina A Rossi2, Fabrizio Vaghi3

  • 1Cardiology Division, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Policlinico di Modena, Modena, Italy. denegriandrea@msn.com.

Cardiology Journal
|February 11, 2020
PubMed

Insights

Cardiac rehabilitation (CR) improves physical function in coronary artery disease (CAD) patients, especially those without diabetes. Diabetic and impaired glucose tolerance (IGT) patients also benefit, particularly from improved blood glucose control.

Area of Science:

  • Cardiology
  • Metabolic Health
  • Rehabilitation Medicine

Background:

  • Cardiac rehabilitation (CR) is linked to reduced mortality in coronary artery disease (CAD) patients.
  • The effects of CR on impaired glucose tolerance (IGT) and diabetes in CAD patients require further investigation.

Purpose of the Study:

  • To assess the impact of CR on pathological risk factors beyond physical exercise improvement in IGT and diabetic CAD patients.

Main Methods:

  • 171 consecutive CAD patients undergoing a 3-month CR program were analyzed.
  • Primary endpoint: improvement in peak workload and VO2-peak.
  • Secondary endpoint: reduction in glycated hemoglobin (HbA1c).

Main Results:

  • Euglycemic patients showed significant improvements in peak workload and VO2-peak compared to diabetic patients.
  • Diabetic patients experienced greater benefits in blood glucose control (HbA1c reduction) than IGT patients.

Conclusions:

  • Multidisciplinary CR enhances physical capacity in CAD patients, particularly euglycemic individuals.
  • Both IGT and diabetic CAD patients can benefit from CR, with improved glucose control being a key outcome for the latter.
  • Larger studies are needed to clarify long-term outcomes.
Abstract

Keywords:
cardiac rehabilitationcardiopulmonary testcoronary artery diseasediabetes mellitusreduced glucose tolerance

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