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Published on: April 28, 2023
Chronic administration of plasma from exercised rats to sedentary rats does not induce redox and metabolic
Georgios Goutianos1, Nikos V Margaritelis1,2, Theodora Sparopoulou1,3
1Department of Physical Education and Sport Science at Serres, Aristotle University of Thessaloniki, Agios Ioannis, 62110, Serres, Greece.
Abstract:
The present study aimed to investigate whether endurance exercise-induced changes in blood plasma composition may lead to adaptations in erythrocytes, skeletal muscle and liver. Forty sedentary rats were randomly distributed into two groups: a group that was injected with pooled plasma from rats that swam until exhaustion and a group that was injected with the pooled plasma from resting rats (intravenous administration at a dose of 2 mL/kg body weight for 21 days). Total antioxidant capacity, malondialdehyde and protein carbonyls were higher in the plasma collected from the exercised rats compared to the plasma from the resting rats. Νo significant difference was found in blood and tissue redox biomarkers and in tissue metabolic markers between rats that received the "exercised" or the "non-exercised" plasma (P > 0.05). Our results demonstrate that plasma injections from exercised rats to sedentary rats do not induce redox or metabolic adaptations in erythrocytes, skeletal muscle and liver.
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