[Updated recommendations for venous thromboembolic prophylaxis in Argentina]

Area of Science:

• Internal Medicine
• Cardiology
• Hematology

Background:

• Venous thromboembolic disease (VTE) in hospitalized adults leads to high morbidity, mortality, and healthcare costs.
• Existing thromboprophylaxis guidelines from 2013 require updating due to emerging strategies and suboptimal adherence.
• A significant knowledge gap exists regarding the practical application of VTE prevention in diverse hospitalized adult populations.

Purpose of the Study:

• To update clinical practice guidelines for VTE prevention in hospitalized adults.
• To incorporate new therapeutic alternatives and strategies for thromboprophylaxis.
• To provide specific recommendations tailored to patient subgroups and available pharmacotherapy in Argentina.

Main Methods:

• Systematic review of recent literature on VTE and thromboprophylaxis.
• Analysis of current consensus and clinical practice guidelines.
• Evaluation of therapeutic options considering drug availability in Argentina.
• Stratification of recommendations based on patient categories (non-surgical, surgical, orthopedic, cancer, pregnant).

Main Results:

• New pharmacological and non-pharmacological VTE prevention strategies have emerged since 2013.
• Suboptimal adherence to existing guidelines remains a challenge.
• Specific recommendations are provided for various adult patient groups, including those with cancer and orthopedic conditions.
• Emphasis is placed on thromboprophylaxis options accessible within the Argentinian healthcare system.

Conclusions:

• Updated recommendations are crucial for optimizing VTE prevention in hospitalized adults.
• Addressing adherence barriers is essential for effective implementation of thromboprophylaxis.
• Tailored strategies considering patient specifics and local drug availability are necessary for managing VTE risk in Argentina.