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Impact of Social Conformity on Ethanol Preference in Wistar Rats
Elena Filatova1, Aleksandr Orlov1, Sergei Afanasyev1
1Laboratory of Behavioral Neuroscience and Pathology, Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Science, Saint Petersburg, Russian Federation.
Introduction:
Social conformity is considered a possible promoter of alcohol use disorder in humans. The goal of this study was to explore the impact of conformity as one of the social factors that might contribute to the alcohol preference in a rat model of ethanol intake.
Methods:
To model social conformity, 105 Wistar rats were group housed (3 animals per cage) with a different number of rats drinking either 10% ethanol or water during daily drinking sessions. Ethanol preference tests were performed.
Results:
Ethanol preference significantly increased if the majority of cage mates received ethanol during drinking sessions. The analysis also showed an increase in the number of approaches to the ethanol bottle versus the water bottle and an increased duration of a single ethanol approach during the 2 bottle preference test in such groups.
Conclusion:
These results demonstrate that social conditions promote the ethanol consumption in the novel conformity model used in this study.
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