Application and Technique of Liquid Crystal-Based Biosensors
Chonglin Luan1, Haipei Luan2, Dawei Luo1
1School of Applied Chemistry and Biotechnology, Shenzhen Polytechnic, Shenzhen 518055, China.
Micromachines
|February 13, 2020
Summary
Liquid crystal biosensors offer a sensitive, portable, and cost-effective method for detecting various molecules. Research highlights advancements in signal amplification and applications for disease diagnostics and chemical analysis.
Area of Science:
- Biotechnology
- Materials Science
- Analytical Chemistry
Background:
- Liquid crystal biosensors leverage changes in liquid crystal molecule orientation upon biomolecular binding.
- These biosensors are recognized for their low cost, high sensitivity, simplicity, effectiveness, and portability.
Purpose of the Study:
- To introduce the fundamental principles and fabrication methods of liquid crystal biosensors.
- To review advancements in signal-amplified technologies for liquid crystal sensing.
- To explore the application of these biosensors in detecting a wide range of targets.
Main Methods:
- Review of existing literature on liquid crystal biosensor design and fabrication.
- Analysis of research progress in signal amplification techniques.
- Compilation of studies demonstrating applications in molecular detection.
Main Results:
- Liquid crystal biosensors demonstrate significant potential for detecting biomolecules, biomolecular activity, and small chemical molecules.
- Signal-amplified technologies have enhanced the sensitivity and scope of liquid crystal sensing.
- Successful applications include the detection of viruses, bacteria, proteins, nucleic acids, and small chemical molecules.
Conclusions:
- Liquid crystal biosensors represent a versatile and promising platform for diverse analytical applications.
- Ongoing research addresses current theoretical and practical challenges to further optimize their performance.
- The field shows strong potential for future development in diagnostics and chemical sensing.
