[Lipoleiomyoma of the uterus--report of a case]

A case of lipoleiomyoma, measuring 4 x 4.5 x 5 cm, in the uterine corpus is reported in a 64-year-old multiparous woman. Histologically, the tumor was mostly composed of mature fatty tissue intermingled with small amount of fibrous and smooth muscle components in an irregularly reticular or clustered pattern. Immunohistochemically fibroblast-like cells around the perivascular areas of the fibrous components were positive in various numbers for S-100 protein, desmin, vimentin, neuron specific enolase, alpha 1-antichymotrypsin and Factor VIII. These results indicated the possibility that the present lipoleiomyoma was derived from multipotential undifferentiated mesenchymal cells, resembling fibroblast-like cells.