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Updated: Dec 28, 2025

High Content Screening Analysis to Evaluate the Toxicological Effects of Harmful and Potentially Harmful Constituents HPHC
Published on: May 10, 2016
Assessment of Essential and Potentially Toxic Elements and Possible Health Risks in Hylocereus undatus and Punica
M Rahman1,2, M A Islam3,4, M M Zaved2
1Institute of Nuclear Science & Technology, Atomic Energy Research Establishment, Ganakbari, Ashulia, Dhaka, 1349, Bangladesh.
Abstract:
This study evaluates essential and toxic element contents in dragon (Hylocereus undatus (Haworth) Britton and Rose) and pomegranate (Punica granatum L.) and possible health risks through the consumption of these fruits. Total concentrations of 15 chemical elements (Al, Br, Ca, Cd, Cl, Cr, Cu, Fe, Hg, K, Mn, Na, Ni, Pb, and Zn) were determined by instrumental neutron activation analysis (INAA) and atomic absorption spectrometry (AAS) techniques. This study indicates that these fruits are a vital source of essential elements for human health. It is observed that Pb concentrations were higher in both fruits whereas Cd concentrations were slightly higher than WHO/FAO tolerable levels only in pomegranate. The estimated daily intake (EDI) of the chemical elements was within the maximum tolerable daily intake (MTDI) values. Furthermore, target hazard quotient (THQ) values were also within the safe level (THQ < 1). However, the calculated target carcinogenic risk (TCR) values of Cd for pomegranate and Cr for dragon fruit were higher than the maximum limit (1.0 × 10-4) for children. Finally, this study will create public awareness about micronutrient contents as well as metal contaminations of the studied fruits.
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