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Serum Calcium Level in Patients with Essential Hypertension.

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This study found that higher serum calcium levels are linked to increased systolic blood pressure in essential hypertensive patients in Bangladesh. Further research is recommended to confirm this association between serum calcium and hypertension.

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Area of Science:

  • Cardiology
  • Clinical Biochemistry
  • Public Health

Background:

  • Hypertension is a major global health risk, particularly prevalent in Bangladesh.
  • The relationship between serum calcium levels and hypertension pathophysiology is debated, with inconsistent findings across studies.
  • Understanding this link is crucial for managing hypertension effectively.

Purpose of the Study:

  • To investigate the association between serum calcium levels and essential hypertension in a Bangladeshi population.
  • To determine if serum calcium concentration correlates with blood pressure readings in hypertensive patients.

Main Methods:

  • A cross-sectional study involving 107 essential hypertensive patients at Shaheed Monsur Ali Medical College and Hospital, Bangladesh.
  • Blood pressure measured per American Heart Association (AHA) protocols; serum calcium, albumin, and creatinine analyzed using a HITACHI analyzer.
  • Data collected via pretested questionnaires and analyzed using SPSS 24.0.

Main Results:

  • The study included 107 patients, predominantly middle-aged, male, urban residents, and overweight/obese.
  • Mean systolic blood pressure (SBP) was 161.21±12.91 mmHg and diastolic blood pressure (DBP) was 98.26±6.31 mmHg.
  • A significant positive linear relationship was observed between serum calcium and SBP (Beta=0.201, p=0.024), with higher SBP in patients with corrected calcium >8.5 mg/dL.

Conclusions:

  • This study reveals a significant association between corrected serum calcium levels and systolic blood pressure in essential hypertensive patients.
  • A notable percentage of patients (23.36%) presented with hypocalcemia.
  • Larger, multicenter studies are recommended to further validate these findings and explore the clinical implications of serum calcium in hypertension management.