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Serum Lipid Profile and Its Association with Newly Diagnosed Hypertensive Patients in Bangladesh
M M Rahman1, M Akhter, M A Rahman
1Dr Md Mahbubor Rahman, Associate Professor, Department of Medicine, Shaheed Monsur Ali Medical College, Dhaka, Bangladesh;
Insights
Newly diagnosed hypertension patients frequently have dyslipidemia, with high levels of total cholesterol, triglycerides, and LDL cholesterol. Low HDL cholesterol was also common, indicating a significant metabolic abnormality burden.
Area of Science:
- Cardiology
- Metabolic Syndrome
- Public Health
Background:
- Clustering of hypertension, dyslipidemia, and metabolic abnormalities contributes to non-communicable diseases, particularly cardiovascular disease.
- Understanding lipid profiles in newly diagnosed hypertensive patients is crucial for early intervention and disease management.
Purpose of the Study:
- To investigate the lipid profile patterns in newly diagnosed hypertensive patients.
- To determine the prevalence of dyslipidemia in this patient group.
Main Methods:
- A cross-sectional study was conducted with 59 newly diagnosed hypertensive patients.
- Data were collected using a pre-structured questionnaire and analyzed with SPSS 24.0.
- Ethical clearance and informed written consent were obtained prior to data collection.
Main Results:
- The study observed a slight male preponderance (54.2%) with an average age of 45 years.
- High prevalence of abnormal lipid levels: 91.5% had elevated total cholesterol, 98.3% elevated triglycerides, and 88.1% elevated LDL cholesterol.
- Low levels of HDL cholesterol were found in 47.5% of patients; almost all patients were obese. No correlation was found between serum lipid profile and blood pressure.
Conclusions:
- Dyslipidemia is highly prevalent in newly diagnosed hypertensive patients in Dhaka, Bangladesh.
- These findings highlight the significant metabolic derangements co-existing with hypertension, necessitating comprehensive management strategies.
Abstract:
Clustering of hypertension, dyslipidemia, and other metabolic abnormalities is increasing the burden of non-communicable diseases, especially cardiovascular disease. The objective of this study was to explore the pattern of lipid profiles in newly diagnosed hypertensive patients attending Shaheed Mansur Ali Medical College, Dhaka, Bangladesh from August 2020 to December 2020. A total of 59 newly diagnosed hypertensive patients were studied through a cross-sectional approach. Prior to the study, ethical clearance was ensured, and informed written consent was obtained. A pre-structured questionnaire was used for data collection. Collected data were analyzed using SPSS 24.0 version. Slight male preponderance (54.2%) was observed along with an average age of 45 years among studied patients. Raised levels of total cholesterol (TC), triglyceride (TG), and low-density lipoprotein (LDL) were observed in 91.5%, 98.3%, and 88.1% of patients accordingly. Low level of high-density lipoprotein (HDL) was observed in 47.5% of the patients. Mean TC, TG, LDL, HDL were 286.11±347.37, 311.74±122.76, 163.27±33.67 and 38.29±6.66 mg/dl, respectively. Almost all patients were obese. There is no correlation between the serum lipid profile and blood pressure of the patients. Dyslipidemia was highly prevalent among newly diagnosed hypertensive patients.
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