Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cancer Prevention02:59

Cancer Prevention

7.5K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
7.5K
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

8.6K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
8.6K
Drugs that Stabilize Microtubules01:15

Drugs that Stabilize Microtubules

2.5K
Microtubules are dynamic structures that undergo cycles of catastrophe and rescue. The microtubules play a central role in cell division by forming the spindle apparatus for segregating the chromosomes. This makes them ideal targets for regulating dividing cells in tumors and malignant cancer cells. Microtubule stabilizing drugs help stabilize the microtubule formation and promote its polymerization. Paclitaxel was the first microtubule stabilizing agent used as anticancer drug in chemotherapy...
2.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Corrigendum to '4-phenyl isothiocyanate modified electrode based on diazonium electrodeposition for heavy metals detection in pharmaceuticals' [Talanta, 295, (2025) 128339 DOI: 10.1016/j.talanta.2025.128339].

Talanta·2026
Same author

4-Phenyl isothiocyanate modified electrode based on diazonium electrodeposition for heavy metals detection in pharmaceuticals.

Talanta·2025
Same author

Optimization of Green Ultrasound-Assisted Extraction of Carotenoids and Tocopherol from Tomato Waste Using NADESs.

Molecules (Basel, Switzerland)·2025
Same author

Valorization of Bioactive Compounds from Lingonberry Pomace and Grape Pomace with Antidiabetic Potential.

Molecules (Basel, Switzerland)·2024
Same author

Curcumin-Based Molecularly Imprinted Polymer Electropolymerized on Single-Use Graphite Electrode for Dipyridamole Analysis.

Molecules (Basel, Switzerland)·2024
Same author

Antioxidant and Antidiabetic Activity of <i>Cornus mas</i> L. and <i>Crataegus monogyna</i> Fruit Extracts.

Molecules (Basel, Switzerland)·2024

Related Experiment Video

Updated: Dec 28, 2025

Establishment of Hepatocarcinoma in BALB/c-nu Mice and Investigation of the Therapeutic Effect of the Sanleng Jiashen Formula
09:03

Establishment of Hepatocarcinoma in BALB/c-nu Mice and Investigation of the Therapeutic Effect of the Sanleng Jiashen Formula

Published on: January 26, 2024

607

Lignans from Medicinal Plants and their Anticancer Effect.

Eugenia Dumitra Teodor1, Veronica Moroeanu1, Gabriel Lucian Radu2

  • 1Centre of Bioanalysis, National Institute of Biological Sciences, Bucharest, Romania.

Mini Reviews in Medicinal Chemistry
|February 13, 2020
PubMed
Summary

Plant lignans show significant potential in cancer prevention and treatment due to their antioxidant and anticarcinogenic properties. This review highlights recent findings on lignans

Keywords:
Medicinal plantsanticancer effectbioavailabilitycytotoxicitylignansmechanism of action

More Related Videos

Author Spotlight: Liujunzi Decoction as a Traditional Chinese Treatment for Coloproctitis Cancer
06:24

Author Spotlight: Liujunzi Decoction as a Traditional Chinese Treatment for Coloproctitis Cancer

Published on: October 13, 2023

1.5K
Author Spotlight: Exploring Salidroside's Molecular Mechanisms in Breast Cancer Treatment
11:13

Author Spotlight: Exploring Salidroside's Molecular Mechanisms in Breast Cancer Treatment

Published on: June 9, 2023

2.1K

Related Experiment Videos

Last Updated: Dec 28, 2025

Establishment of Hepatocarcinoma in BALB/c-nu Mice and Investigation of the Therapeutic Effect of the Sanleng Jiashen Formula
09:03

Establishment of Hepatocarcinoma in BALB/c-nu Mice and Investigation of the Therapeutic Effect of the Sanleng Jiashen Formula

Published on: January 26, 2024

607
Author Spotlight: Liujunzi Decoction as a Traditional Chinese Treatment for Coloproctitis Cancer
06:24

Author Spotlight: Liujunzi Decoction as a Traditional Chinese Treatment for Coloproctitis Cancer

Published on: October 13, 2023

1.5K
Author Spotlight: Exploring Salidroside's Molecular Mechanisms in Breast Cancer Treatment
11:13

Author Spotlight: Exploring Salidroside's Molecular Mechanisms in Breast Cancer Treatment

Published on: June 9, 2023

2.1K

Area of Science:

  • Medicinal Chemistry
  • Pharmacology
  • Natural Products Chemistry

Background:

  • Traditional medicine extensively utilizes plants for treating various ailments.
  • Phenolic compounds, including lignans, are key secondary metabolites in medicinal plants.
  • Lignans possess significant antioxidant, anticarcinogenic, antimutagenic, and anti-estrogenic properties.

Purpose of the Study:

  • To review recent literature on plant lignans and their derivatives in cancer prevention and treatment.
  • To summarize in vitro and in vivo findings regarding lignan efficacy.
  • To elucidate the mechanistic aspects of lignan action in cancer therapy.

Main Methods:

  • Comprehensive literature search of recent studies.
  • In vitro assays to assess biological activities.
  • In vivo studies to evaluate therapeutic effects in animal models.

Main Results:

  • Plant lignans and their derivatives demonstrate promising anticancer activities.
  • Evidence supports their role in cancer prevention and treatment across various assessments.
  • Mechanistic studies reveal key pathways targeted by lignans.

Conclusions:

  • Plant lignans represent a valuable class of natural compounds for cancer chemoprevention and therapy.
  • Further research into lignan derivatives could lead to novel anticancer drugs.
  • Understanding lignan mechanisms can optimize their clinical application.