Jove
Visualize
Contact Us

Related Concept Videos

Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

304
Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
304
Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

603
Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
603
Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

252
Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
252
Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

373
Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
373
Mitral Regurgitation I: Introduction01:20

Mitral Regurgitation I: Introduction

309
Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
309
Pathophysiology of Heart Failure01:17

Pathophysiology of Heart Failure

2.6K
Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
2.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Influence of inflammatory and reninangiotensin system gene polymorphisms ACE2 rs2285666, IL1A rs1800587, and TNF rs1800629 on COVID-19 severity and the persistence of symptoms in the post-COVID-19 phase: a cross-sectional study.

Einstein (Sao Paulo, Brazil)·2026
Same author

Fundamentals of Acute Pericarditis: State of the Art.

Arquivos brasileiros de cardiologia·2026
Same author

Spatiotemporal trends and regional inequities in preeclampsia and eclampsia in Brazil, 2008-2023.

Pregnancy hypertension·2026
Same author

Brazilian Dialysis Survey 2024.

Jornal brasileiro de nefrologia·2026
Same author

Subclinical Hypothyroidism as a Risk for Coronary Artery Bypass Grafting.

Cardiovascular therapeutics·2026
Same author

Diastolic dysfunction in primary care: medical and nursing interlocutions.

Revista brasileira de enfermagem·2025
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Dec 28, 2025

A Rat Model of Pressure Overload Induced Moderate Remodeling and Systolic Dysfunction as Opposed to Overt Systolic Heart Failure
07:13

A Rat Model of Pressure Overload Induced Moderate Remodeling and Systolic Dysfunction as Opposed to Overt Systolic Heart Failure

Published on: April 30, 2020

6.8K

Left Ventricular Remodeling Patterns in Primary Healthcare.

Roberto de Castro Meirelles de Almeida1, Antonio José Lagoeiro Jorge1, Maria Luiza Garcia Rosa1

  • 1Curso de Pós-Graduação em Ciências Cardiovasculares da Universidade Federal Fluminense (UFF), Niterói, RJ - Brazil.

Arquivos Brasileiros De Cardiologia
|February 13, 2020
PubMed
Summary

Left ventricular remodeling (LVR) affects one-third of adults and is linked to heart failure risk. Altered albumin/creatinine ratio in urine is associated with eccentric hypertrophy, suggesting early cardiac and renal dysfunction.

More Related Videos

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography
06:34

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography

Published on: October 28, 2020

4.5K
Permanent Ligation of the Left Anterior Descending Coronary Artery in Mice: A Model of Post-myocardial Infarction Remodelling and Heart Failure
09:37

Permanent Ligation of the Left Anterior Descending Coronary Artery in Mice: A Model of Post-myocardial Infarction Remodelling and Heart Failure

Published on: December 2, 2014

28.5K

Related Experiment Videos

Last Updated: Dec 28, 2025

A Rat Model of Pressure Overload Induced Moderate Remodeling and Systolic Dysfunction as Opposed to Overt Systolic Heart Failure
07:13

A Rat Model of Pressure Overload Induced Moderate Remodeling and Systolic Dysfunction as Opposed to Overt Systolic Heart Failure

Published on: April 30, 2020

6.8K
Evaluation of Left Ventricular Structure and Function using 3D Echocardiography
06:34

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography

Published on: October 28, 2020

4.5K
Permanent Ligation of the Left Anterior Descending Coronary Artery in Mice: A Model of Post-myocardial Infarction Remodelling and Heart Failure
09:37

Permanent Ligation of the Left Anterior Descending Coronary Artery in Mice: A Model of Post-myocardial Infarction Remodelling and Heart Failure

Published on: December 2, 2014

28.5K

Area of Science:

  • Cardiology
  • Nephrology
  • Echocardiography

Background:

  • Left ventricular remodeling (LVR) is a significant predictor of adverse non-fatal and fatal cardiovascular outcomes.
  • Understanding the geometric patterns of LVR is crucial for risk stratification and management.

Purpose of the Study:

  • To characterize the geometric patterns of left ventricular remodeling (LVR) in a Brazilian population.
  • To investigate the associations between LVR patterns and clinical/laboratory variables.

Main Methods:

  • A cross-sectional study involving 636 individuals aged 45-99 years in Rio de Janeiro, Brazil.
  • Evaluations included clinical assessment, laboratory tests, electrocardiogram, and tissue Doppler echocardiography (TDE).
  • Statistical analyses used Kruskal-Wallis, Pearson's Chi-square, and logistic regression to assess associations with LVR patterns (normal geometry, concentric remodeling, concentric hypertrophy, eccentric hypertrophy).

Main Results:

  • The prevalence of altered left ventricular geometry was 33%.
  • Eccentric hypertrophy (EH) was the most common altered pattern (29%), followed by concentric hypertrophy (2%) and concentric remodeling (2%).
  • Gender, age, education level, and albumin/creatinine ratio (A/C) were independently associated with the likelihood of EH.

Conclusions:

  • Approximately one-third of the study cohort exhibited left ventricular remodeling, placing them at risk for heart failure.
  • An altered urinary albumin/creatinine ratio was linked to eccentric hypertrophy, suggesting an early interplay between cardiac and renal dysfunction.