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Characterization of Bilateral Parietal Thinning.
Paymon Sanati-Mehrizy1, Francis D Graziano1, Thomas Naidich2
1Division of Plastic and Reconstructive Surgery.
The Journal of Craniofacial Surgery
|February 13, 2020
Summary
This study introduces a new grading system for bilateral parietal thinning (BPT), a rare condition. The system correlates with BPT severity and progression, noting age and hypertension as risk factors.
Area of Science:
- Radiology
- Neurosurgery
- Medical Imaging
Background:
- Bilateral parietal thinning (BPT) is an uncommon condition of the skull.
- It can lead to significant patient morbidity, including pain.
- A novel grading system for BPT is needed for better characterization.
Purpose of the Study:
- To define and characterize a novel grading system for bilateral parietal thinning (BPT).
- To correlate this grading system with quantitative measurements of BPT.
- To identify risk factors associated with BPT progression.
Main Methods:
- Retrospective analysis of coronal CT scans from 43 patients with BPT.
- Anatomic measurements included thinning ratio and defect width.
- Patient demographics and comorbidities were collected and analyzed.
Main Results:
- The novel grading scheme significantly correlated with thinning ratio and width (P < 0.001).
- Increasing age was the only independent risk factor for thinning ratio (P=0.044).
- Increasing age (P=0.024) and hypertension (P=0.025) were significant risk factors for defect size. Progressive thinning was observed over time.
Conclusions:
- A novel, quantitatively-characterized grading scheme for BPT is proposed.
- BPT thinning is associated with increasing age, while defect width is linked to age and hypertension.
- This grading system aids in diagnosing, classifying, and monitoring BPT.

