Related Experiment Video
Updated: Dec 28, 2025

Investigating the Neural Mechanisms of Aware and Unaware Fear Memory with fMRI
Published on: October 6, 2011
Tackling fear: Beyond associative memory activation as the only determinant of fear responding
Yannick Boddez1, Agnes Moors2, Gaëtan Mertens3
1Department of Experimental Clinical and Health Psychology, Ghent University, Belgium; Centre for the Psychology of Learning and Experimental Psychopathology, KU Leuven, Leuven, Belgium; Department of Clinical Psychology and Experimental Psychopathology, University of Groningen, Groningen, the Netherlands.
Abstract:
For decades already, the human fear conditioning paradigm has been used to study and develop treatments for anxiety disorders. This research is guided by theoretical assumptions that, in some cases indirectly, stem from the tradition of association formation models (e.g., the Rescorla-Wagner model). We argue that one of these assumptions - fear responding as a monotonic function of the associative activation of aversive memory representations - restricts the types of treatment that the research community currently considers. We discuss the importance of this assumption in the context of research on extinction-enhancing and reconsolidation interference techniques. While acknowledging the merit of this research, we argue that unstrapping the straitjacket of this assumption can lead to exploring new directions for utilizing fear conditioning procedures in treatment research. We discuss two determinants of fear responding other than associative memory activation. First, fear responding might also depend on relational information. Second, a recent goal-directed emotion theory suggests that goals might be the primary determinant of the response pattern characterized as fear.
Related Concept Videos
Role of Amygdala in Memory
One of the...
Functional Brain Systems: Limbic System
Preparedness and Phobias
Associative Learning
Classical conditioning, also known...
Physiological Theories: Cannon-Bard Theory of Emotion
Upon perceiving a stimulus, such as a dangerous...
Classical Conditioning in Daily Life
John B. Watson and Rosalie Rayner famously demonstrated the development of fear through classical conditioning in their experiment with Little Albert. They paired the...

