Dammarane triterpenoid glycosides in Bacopa monnieri: A review on chemical diversity and bioactivity
Pamita Bhandari1, Nitisha Sendri1, Shinde Bhagatsing Devidas1
1Natural Product Chemistry & Process Development, CSIR-Institute of Himalayan Bioresource Technology, Palampur, India.
Abstract:
Bacopa monnieri (L.) is a reputed medicinal herb in traditional system of medicine of India, where it is used as nervine tonic to sharpen intellect and memory. This review discusses chemical characterization of dammarane triterpenoid glycosides which are well accepted for improvement in memory and for potential pharmacological activities. In addition, this review provides information on the chemical composition of specialized metabolites of B. monnieri and in the formulations by different analytical techniques. This comprehensive review covers literature up to 2019 with an emphasis on structural characterization of dammarane triterpenoid glycosides by spectroscopic techniques, chemical composition by analytical methods and pharmacological activities.
Related Concept Videos
Structure-Activity Relationships and Drug Design
SAR studies the intricate relationship between a drug's chemical structure and biological activity. It focuses on understanding how modifications to a drug's structure can influence...
Direct-Acting Cholinergic Agonists: Chemistry and Structure-Activity Relationship
The direct-acting...
Cholinergic Antagonists: Chemistry and Structure-Activity Relationship
Drugs Affecting Neurotransmitter Synthesis
Bioavailability Enhancement: Drug Stability Enhancement and GI Retention
Therapeutic Drug Monitoring: Drug Analysis Methods


