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Published on: April 19, 2017
Primary cutaneous Aspergillus fumigatus infection in immunocompetent host
Pradeep Kumar Mada1, Daniel Alexander Saldaña Koppel2, Majd Al Shaarani3
1Infectious Diseases, Louisiana State University Health Sciences Center Shreveport, Shreveport, Louisiana, USA pradeepsomc@gmail.com.
Abstract:
Primary cutaneous aspergillosis (PCA) occurs through inoculation of fungal spores directly into the skin from the environment through disrupted skin such as in burns, surgery or penetrating trauma patients. Most cases reported in literature were in the immunocompromised, rarely in immunocompetent patients. The characteristic lesion of cutaneous aspergillosis is a black eschar on a red plaque, or nodule at the site of skin injury. The diagnosis of PCA can be made by identifying hyphal forms on routine H&E staining or special stains such as periodic acid-Schiff or Gomori methenamine-silver stains on skin biopsy and by fungal cultures. We report a case of an 80-year-old farmer who developed cutaneous aspergillosis after a surgical procedure without any systemic spread. The diagnosis was made by histopathology and tissue fungal cultures. He was treated with incision and drainage followed by oral voriconazole for 4 weeks; which led to clinical recovery.
Insights
Primary cutaneous aspergillosis (PCA), a fungal skin infection, can occur in immunocompetent individuals. This case highlights successful treatment of PCA in an elderly farmer using surgical drainage and oral antifungal medication.
Area of Science:
- Dermatology
- Mycology
- Infectious Diseases
Background:
- Primary cutaneous aspergillosis (PCA) is a rare fungal infection typically affecting the skin via direct inoculation.
- While often seen in immunocompromised patients, PCA can occur in immunocompetent individuals, particularly after skin trauma.
- Characteristic lesions include a black eschar on an erythematous plaque or nodule at the injury site.
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