Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

184
Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
184
The Periodic Table and Organismal Elements00:57

The Periodic Table and Organismal Elements

199.0K
Overview
199.0K
The Periodic Table and Organismal Elements01:27

The Periodic Table and Organismal Elements

22.1K
Elements are the smallest units of matter that cannot be broken down further by chemical processes. There are 118 known elements, but not all of these are naturally occurring, and only a few of them are essential for life. Living matter is composed primarily of carbon, nitrogen, hydrogen, and oxygen, with smaller amounts of other elements like calcium, phosphorus, potassium, and sulfur. Other elements are also necessary for life but only in trace amounts.
Periodic Table Provides Information...
22.1K
Pulmonary Function Tests01:25

Pulmonary Function Tests

658
Pulmonary Function Tests (PFTs)
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
PFTs involve using a spirometer, a...
658
Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

204
Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight,...
204
Pharmacokinetics in Pediatric Patients: Drug Metabolism01:24

Pharmacokinetics in Pediatric Patients: Drug Metabolism

146
In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses...
146

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinical subphenotypes in septic patients with new-onset atrial fibrillation: validation and parsimonious classifier model development.

BMC medical informatics and decision making·2026
Same author

Early identification of severe Mycoplasma pneumoniae pneumonia in children: A retrospective model development study.

Respiratory medicine·2026
Same author

Vaccination status of children with special health-care needs visiting a vaccination consultation clinic of a pediatric hospital in Wuxi, China, from 2020 to 2023: A cross-sectional study.

Human vaccines & immunotherapeutics·2026
Same author

Key oxidized lipid metabolites in pancreatic cancer tissue and metastasis based on metabolomics analysis.

Biochemical and biophysical research communications·2025
Same author

Medicarpin reduces cisplatin resistance and causes apoptosis by inhibiting the AKT/Bcl2 pathway in breast cancer.

Naunyn-Schmiedeberg's archives of pharmacology·2025
Same author

The effect of periodontal status in the associations between socioeconomic status and cognitive performance: a mediation analysis in older adults.

Frontiers in aging neuroscience·2025

Related Experiment Video

Updated: Dec 28, 2025

Atomic Absorbance Spectroscopy to Measure Intracellular Zinc Pools in Mammalian Cells
13:04

Atomic Absorbance Spectroscopy to Measure Intracellular Zinc Pools in Mammalian Cells

Published on: May 16, 2019

39.1K

Sex Difference Between Trace Elements and Pulmonary Functions in Children.

Zhenzhen Pan1, Xiaojuan Zhang1, Yu Hui1

  • 1Department of Pediatric Respiratory, Wuxi Children's Hospital, Wuxi, 214023, Jiangsu Province, People's Republic of China.

Biological Trace Element Research
|February 16, 2020
PubMed
Summary
This summary is machine-generated.

Zinc deficiency is linked to poorer lung function and higher IgE levels in boys, suggesting trace element screening could help prevent childhood asthma. This study highlights zinc

Keywords:
ChildrenIgEMagnesiumPulmonary functionSeleniumZinc

More Related Videos

Author Spotlight: Integrating Alveolar-Capillary Reserve Measurements in Exercise Adaptation and Therapeutic Strategies
08:44

Author Spotlight: Integrating Alveolar-Capillary Reserve Measurements in Exercise Adaptation and Therapeutic Strategies

Published on: February 2, 2024

1.2K
Measurement of Tissue Non-Heme Iron Content using a Bathophenanthroline-Based Colorimetric Assay
05:08

Measurement of Tissue Non-Heme Iron Content using a Bathophenanthroline-Based Colorimetric Assay

Published on: January 31, 2022

5.4K

Related Experiment Videos

Last Updated: Dec 28, 2025

Atomic Absorbance Spectroscopy to Measure Intracellular Zinc Pools in Mammalian Cells
13:04

Atomic Absorbance Spectroscopy to Measure Intracellular Zinc Pools in Mammalian Cells

Published on: May 16, 2019

39.1K
Author Spotlight: Integrating Alveolar-Capillary Reserve Measurements in Exercise Adaptation and Therapeutic Strategies
08:44

Author Spotlight: Integrating Alveolar-Capillary Reserve Measurements in Exercise Adaptation and Therapeutic Strategies

Published on: February 2, 2024

1.2K
Measurement of Tissue Non-Heme Iron Content using a Bathophenanthroline-Based Colorimetric Assay
05:08

Measurement of Tissue Non-Heme Iron Content using a Bathophenanthroline-Based Colorimetric Assay

Published on: January 31, 2022

5.4K

Area of Science:

  • Pediatric Pulmonology
  • Environmental Health
  • Nutritional Science

Background:

  • Trace element deficiencies are implicated in asthma development.
  • The specific roles of blood zinc (Zn), selenium (Se), and magnesium (Mg) in pediatric pulmonary function require further elucidation.

Purpose of the Study:

  • To investigate the association between blood levels of zinc, selenium, and magnesium and pulmonary function in healthy children.
  • To explore the relationship between these trace elements and serum total IgE levels in relation to pulmonary function.

Main Methods:

  • A cross-sectional study involving 202 healthy children in Wuxi, China.
  • Measurement of pulmonary function (FVC, FEV1), blood trace element levels (Zn, Se, Mg) via ICP-MS, and serum total IgE.
  • Analysis using multiple linear regression models, stratified by sex.

Main Results:

  • A positive association was observed between blood zinc levels and pulmonary function (FVC, FEV1) in boys.
  • Blood zinc levels were negatively associated with serum total IgE in boys.
  • No significant associations were found for selenium or magnesium, nor for zinc in girls.

Conclusions:

  • Zinc deficiency is significantly related to impaired pulmonary function in children, particularly boys.
  • Blood zinc levels may serve as a biomarker for respiratory health in children.
  • Screening for trace element status, specifically zinc, could be a potential strategy for reducing asthma risks in children.