Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Drug Classes and Categories01:25

Drug Classes and Categories

2.7K
Drugs can be classified according to their chemical composition or their intended therapeutic application. For instance, anti-infective agents that possess the ability to eliminate pathogens or suppress their growth and reproduction can be grouped based on the organisms they target or their chemical structure. Furthermore, drugs can be divided into prescription, nonprescription, or controlled substances. Prescription medications, such as antibiotics, require oversight from a licensed healthcare...
2.7K
Chemotherapy-Induced Nausea and Vomiting: Cannabinoids01:21

Chemotherapy-Induced Nausea and Vomiting: Cannabinoids

608
Tetrahydrocannabinol (THC) is a phytocannabinoid that primarily interacts with the CB1 receptor, a type of G protein-coupled receptor (GPCR) predominantly in and around the chemoreceptor trigger zone (CTZ) and emetic center. THC also blocks the serotonin receptor activity in the dorsal vagal complex (DVC) by inhibiting serotonin release. THC exerts its anti-emetic effects through these interactions, which are beneficial for patients undergoing chemotherapy.
Two synthetic agonists of THC,...
608
Drug Control Governance: Regulatory Bodies and Their Impact01:03

Drug Control Governance: Regulatory Bodies and Their Impact

428
Drug control governance involves the oversight and regulation of pharmaceuticals to ensure their safety and efficacy while preventing illegal drug use and trafficking. Regulatory bodies, including the US Food and Drug Administration (FDA) and the European Union's European Medicines Agency (EMA), play a central role in this process. These agencies evaluate the safety and efficacy of drugs before they can be marketed. They fund clinical trials and assess the benefits and risks associated with...
428
Drug Regulation01:25

Drug Regulation

2.6K
Drug regulation encompasses the management of drug usage by evaluating its safety and efficacy through assessments conducted by regulatory authorities. Regrettably, the history of drug regulation is marred by several catastrophic events. One such incident is the Elixir Sulfanilamide tragedy, in which the toxic compound diethyl glycol was included in a sweet-tasting medication, leading to numerous fatalities. This event prompted the enactment of the Food, Drug, and Cosmetic Act in 1938. Under...
2.6K
CNS Stimulants: Cocaine, Amphetamines and Cannabinoids01:24

CNS Stimulants: Cocaine, Amphetamines and Cannabinoids

685
CNS stimulants, such as cocaine, amphetamines, and cannabinoids, have varying structures and mechanisms of action that lead to different therapeutic effects and side effects. Cocaine, with its molecular formula C17H21NO4, is a tropane alkaloid and a tertiary amino compound. It has two chemical forms: the hydrochloride salt and the "freebase." The former is in powder form, while the latter involves removing the hydrochloride salt to create a form that can be smoked. Cocaine exerts its...
685
Drug Nomenclature01:17

Drug Nomenclature

2.8K
During the development of a new pharmaceutical, the manufacturer initially assigns a code name to the drug. Once approved, the drug receives a United States Adopted Name (USAN)—a generic, nonproprietary designation. Upon being listed in the United States Pharmacopeia, this nonproprietary name becomes the drug's official name. Additionally, the manufacturer assigns a proprietary name or trademark, which serves as the brand name under which the drug is marketed. It is worth noting that...
2.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cyclic Peptides as Modulators of Protein-Protein Interactions: A Survival Guide from Discovery Platforms to AI-Driven Design.

International journal of molecular sciences·2026
Same author

Plasminogen Recruitment by <i>Staphylococcus aureus</i> SdrC Reveals a Tractable Antivirulence Target.

ACS infectious diseases·2026
Same author

Transformation-Aware Molecular Networking for Interpretation of Untargeted LC-HRMS Data.

ACS measurement science au·2026
Same author

The Differential Redox Resilience of Alvelestat and Sivelestat: A Mechanistic Hypothesis for Inhibitor Performance Under Oxidative Stress.

Molecules (Basel, Switzerland)·2026
Same author

Targeting Autoinducer‑2 Quorum Sensing: Novel Inhibitors Attenuate Virulence in <i>Staphylococcus aureus</i> and <i>Pseudomonas aeruginosa</i>.

ACS omega·2026
Same author

Autoradiography and preclinical PET studies with radiolabeled asyn-44 and ACI-12589 for imaging α-synuclein.

Journal of Parkinson's disease·2026

Related Experiment Video

Updated: Dec 28, 2025

Oromucosal as an Alternative Method for Administration of Cannabis Products in Rodents
03:43

Oromucosal as an Alternative Method for Administration of Cannabis Products in Rodents

Published on: August 22, 2025

303

Is cannabidiol a scheduled controlled substance? Origin makes the difference.

Cinzia Citti1, Pasquale Linciano2, Giuseppe Cannazza3

  • 1Mediteknology, Spin-off of the National Council of Research, Via Arnesano, 73100 Lecce, Italy; CNR NANOTEC, Institute of Nanotechnology, Via Monteroni, 73100, Lecce, Italy; Department of Life Sciences, University of Modena and Reggio Emilia, Via G. Campi 103, 41125 Modena, Italy.

Drug Discovery Today
|February 17, 2020
PubMed
Summary

Cannabidiol (CBD), a hemp compound, has varying legal statuses based on its origin. Distinguishing between extracted and synthetic CBD is crucial for regulatory and chemical clarity, with impurity profiles offering a potential method.

More Related Videos

Tobacco Hornworm as an Insect Model System for Cannabinoid Pre-clinical Studies
05:25

Tobacco Hornworm as an Insect Model System for Cannabinoid Pre-clinical Studies

Published on: December 29, 2021

2.8K
Administration of &#916;9-Tetrahydrocannabinol (THC) in Adolescent and Adult Mice
07:51

Administration of Δ9-Tetrahydrocannabinol (THC) in Adolescent and Adult Mice

Published on: August 1, 2025

712

Related Experiment Videos

Last Updated: Dec 28, 2025

Oromucosal as an Alternative Method for Administration of Cannabis Products in Rodents
03:43

Oromucosal as an Alternative Method for Administration of Cannabis Products in Rodents

Published on: August 22, 2025

303
Tobacco Hornworm as an Insect Model System for Cannabinoid Pre-clinical Studies
05:25

Tobacco Hornworm as an Insect Model System for Cannabinoid Pre-clinical Studies

Published on: December 29, 2021

2.8K
Administration of &#916;9-Tetrahydrocannabinol (THC) in Adolescent and Adult Mice
07:51

Administration of Δ9-Tetrahydrocannabinol (THC) in Adolescent and Adult Mice

Published on: August 1, 2025

712

Area of Science:

  • Pharmacology
  • Organic Chemistry
  • Regulatory Science

Background:

  • Cannabidiol (CBD) is a primary cannabinoid found in hemp, recognized for its diverse pharmacological activities.
  • Legal classifications differ significantly between plant-extracted CBD (a controlled substance) and chemically synthesized CBD (not controlled).
  • Extracted CBD is notably absent from the European CosIng cosmetic ingredient database.

Purpose of the Study:

  • To address the regulatory and chemical confusion surrounding extracted versus synthetic CBD.
  • To provide clarity on the distinct characteristics of different CBD forms.
  • To identify reliable methods for differentiating the origin of CBD.

Main Methods:

  • Comparative analysis of chemical impurity profiles between naturally extracted and synthetically produced CBD.
  • Review of current regulatory frameworks and database inclusions (e.g., CosIng) concerning CBD.

Main Results:

  • Significant differences exist in the impurity profiles of synthetic and natural CBD.
  • These distinct impurity profiles may serve as the primary analytical means to determine CBD origin.

Conclusions:

  • Clarification of CBD's regulatory and chemical status is urgently needed.
  • Impurity profiling presents a viable chemical approach to distinguish between extracted and synthetic CBD.
  • Further research into analytical methods for CBD origin determination is warranted.