Related Experiment Video
Updated: Dec 28, 2025
11:51
Combining Behavioral Endocrinology and Experimental Economics: Testosterone and Social Decision Making
Published on: March 2, 2011
15.5K
Economic vulnerability and payment for research participation
Luke Gelinas1,2, Sarah A White2, Barbara E Bierer2,3,4
1Advarra IRB, Columbia, MD, USA.
Clinical Trials (London, England)
|February 18, 2020
Summary
Paying economically vulnerable individuals in clinical research is ethically justified when specific conditions are met. This ensures fairness and avoids undue influence, even in low-resource settings.
Area of Science:
- Bioethics
- Clinical Research Ethics
- Socioeconomic Determinants of Health
Background:
- Limited attention has been paid to the ethical implications of compensating economically vulnerable populations in research.
- Economically vulnerable individuals are present across diverse disease groups and study populations, including in low- and middle-income countries and impoverished regions.
Purpose of the Study:
- To analyze the ethical considerations of paying economically vulnerable individuals for research participation.
- To determine appropriate payment rates and practices for this population.
- To address concerns regarding undue influence and unjust representation in clinical research.
Main Methods:
- Analysis of ethical issues concerning payment to research participants, with a specific focus on economically vulnerable individuals.
- Examination of four key areas: risk of undue influence, potential for unjust influence or disproportionate representation, fairness considerations, and appropriate compensation rates.
Main Results:
- The risk of undue influence may be heightened for economically vulnerable individuals.
- Concerns exist regarding the potential for "unjust influence" and disproportionate representation of poorer individuals in research.
- Fairness considerations support the payment of economically vulnerable populations.
- Appropriate compensation rates require careful determination.
Conclusions:
- Payment to economically vulnerable populations in research is ethically justifiable and desirable under specific conditions.
- Ethical frameworks must address the unique challenges and vulnerabilities of these populations.
- Ensuring fairness and avoiding exploitation are paramount when compensating research participants from lower socioeconomic backgrounds.
More Related Videos
13:04Measuring the Subjective Value of Risky and Ambiguous Options using Experimental Economics and Functional MRI Methods
Published on: September 19, 2012
12.4K
06:16Involving Individuals with Developmental Language Disorder and Their Parents/Carers in Research Priority Setting
Published on: June 6, 2020
4.2K
Related Concept Videos
01:56Ethics in Research
25.3K
Today, scientists agree that good research is ethical in nature and is guided by a basic respect for human dignity and safety. However, this has not always been the case. Modern researchers must demonstrate that the research they perform is ethically sound.
25.3K
01:23Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
340
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
340
02:20Longitudinal Research
13.0K
Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...
13.0K
01:15Bioavailability Study Design: Healthy Subjects Versus Patients
92
Bioavailability studies are essential for evaluating a drug's therapeutic efficacy and understanding its absorption patterns under various physiological conditions. Conducting such studies on target patient populations provides more relevant data by simulating real-world disease states. However, practical challenges often necessitate the use of young, healthy adult volunteers as study subjects.Patients may exhibit altered drug absorption patterns due to the effects of the disease itself,...
92
01:21EPS and iPS Cells in Disease Research
3.2K
Embryonic and induced pluripotent stem cells are excellent models for disease research because of their ability to self-renew and differentiate into most cell types. Somatic cells from a patient are isolated and reprogrammed into induced pluripotent stem cells or iPSCs. These iPSCs are later differentiated into the desired cell type, which mirrors the diseased cell of the patient. In this way, disease models have been created for investigating diseases such as Down syndrome, type I diabetes,...
3.2K
02:07Blind Procedures
12.7K
Ideally, the people who observe and record the children’s behavior are unaware of who was assigned to the experimental or control group, in order to control for experimenter bias. Experimenter bias refers to the possibility that a researcher’s expectations might skew the results of the study. Remember, conducting an experiment requires a lot of planning, and the people involved in the research project have a vested interest in supporting their hypotheses. If the observers knew which...
12.7K