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Published on: May 1, 2015
Types of paraproteinemia in patients with multiple myeloma: A cross-sectional study
Saira Parveen Sheikh1, Syed Muhammad Irfan1, Sadia Sultan Sheikh1
1Department of Hematology, Liaquat National Hospital, Karachi, Pakistan.
Objective:
To determine the types of paraproteins in patients with multiple myeloma in a tertiary care setting.
Methods:
The cross-sectional study was conducted at the Liaquat National Hospital, Karachi, from November 2015 to May 2016, and comprised patients with multiple myeloma selected using consecutive, non-probability sampling technique. Detailed history was taken and immunofixation assay was conducted to assess the type of paraproteins in the patients. Data was recorded on a proforma and analysed using SPSS 22.
Results:
Of the 87 patients, 62(71.3%) were males and 25(28.7%) were females. The overall mean age was 57.41±10.53 years. Of the total, 52(71.3%), patients had Immunoglobulin G kappa and 61(70%) had Immunoglobulin A kappa paraprotein.
Conclusions:
The most common types of paraprotein was found to be Immunoglobulin G kappa followed by Immunoglobulin A kappa.
