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Updated: Dec 28, 2025

Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance
Published on: June 6, 2025
MRI-guided pelvic lymph node biopsy via transrectal approach in prostate cancer
Christian Hague1, Luke P O'Connor1, Alex Z Wang1
1Urologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Abstract:
Lymph node assessment in prostate cancer is most commonly performed at the time of radical prostatectomy. We present the case of pre-operative pelvic lymph node sampling with the use of MRI/TRUS fusion-guided biopsy at the time of prostate biopsy. Lymph node pathology revealed metastatic, poorly differentiated prostate cancer, concurrent with Gleason 4 + 5 disease showing perineural invasion. The use of MRI fusion guided biopsy for nodal sampling may be an effective method pre-operative staging and treatment planning for prostate adenocarcinoma.

