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Updated: Dec 28, 2025
Tissue Engineering of the Intestine in a Murine Model
Published on: December 1, 2012
Advances in chronic intestinal failure management and therapies
Liat Deutsch1, Anabelle Cloutier2, Simon Lal2,3
1The Department of Gastroenterology and Liver diseases, Tel-Aviv Sourasky Medical Centre and Sackler Faculty of Medicine, Tel-Aviv University, Israel.
Purpose Of Review:
To summarize changes and recent advances in therapies for chronic intestinal failure (CIF).
Recent Findings:
In the last few years, the management of CIF has significantly improved through better prevention and treatment of catheter-related bloodstream infections (CRBSIs) and intestinal failure-associated liver disease (IFALD), as well as improved enteral autonomy by using small bowel growth factors in selected patients. This may have been reflected by a recent reduction in small bowel transplantations.
Summary:
Although CIF management has become more established and effective, the long-term implications of parenteral nutrition still place substantial burden on patients such that further work is required to improve patients' quality of life as well as continued efforts to reduce complications relating to CIF management.
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