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Published on: September 22, 2023
Turbinate hypertrophy in children with allergic rhinitis: clinical relevance
Giorgio Ciprandi1, Maria Angela Tosca2, Fabio Gallo3
1Allergy Clinic, Casa di Cura Villa Montallegro, Genoa, Italy. gio.cip@libero.it.
Insights
Turbinate hypertrophy (TH) is common in children with allergic rhinitis (AR). Age, male gender, and recurrent acute otitis media (RAOM) are significantly associated with TH in pediatric AR patients.
Area of Science:
- Pediatric Allergy and Immunology
- Otolaryngology
- Pediatric Health
Background:
- Allergic rhinitis (AR) is a prevalent childhood immune disorder, affecting up to 40% of children.
- Turbinate hypertrophy (TH) is a key indicator of AR and frequently causes nasal obstruction.
- Understanding factors associated with TH is crucial for managing pediatric AR.
Purpose of the Study:
- To identify factors associated with turbinate hypertrophy (TH) in children diagnosed with allergic rhinitis (AR).
Main Methods:
- A cohort of 544 children with AR was studied.
- Turbinate hypertrophy (TH) was diagnosed in the participants.
- Multivariate analysis was employed to determine associations between TH and various factors.
Main Results:
- Turbinate hypertrophy (TH) was diagnosed in 80.81% of the pediatric allergic rhinitis (AR) cohort.
- Significant associations were found between TH and age (p=0.0219), male gender (p<0.0001), and recurrent acute otitis media (RAOM) (p=0.0003).
Conclusions:
- Turbinate hypertrophy (TH) is highly prevalent in children with allergic rhinitis (AR).
- Age, male gender, and a history of recurrent acute otitis media (RAOM) are significant predictors of TH in this population.
- These findings highlight important clinical associations for managing pediatric AR and TH.
Abstract:
Allergic rhinitis (AR) is the most common immune-mediated disorder in childhood as it may affect up to 40% of children. Turbinate hypertrophy (TH) is an important sign as reliably predicts AR both in children and adults. Consistently, nasal obstruction is a very common symptom in AR patients and is closely linked with turbinate hypertrophy. This study investigated 544 (304 males) children with AR to define factors associated with TH. TH was diagnosed in 438 (80.81%) AR children. The multivariate analysis demonstrated a significant association between age, male gender, and recurrent acute otitis media (RAOM), and TH (p-values: 0.0219, <0.0001, and 0.0003, respectively; OR 0.87, 3.97, and 0.22 respectively). In conclusion, this real-life study showed that TH was very frequent in children with AR and age, male gender, and RAOM were significantly associated with TH.
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