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Intra-articular apatite deposition in mixed connective tissue disease: crystallographic and technetium scanning
C W Hutton1, P J Maddison, A J Collins
1Royal National Hospital for Rheumatic Diseases, Bath.
Annals of the Rheumatic Diseases
|December 1, 1988
Abstract:
An acute arthritis in a patient with mixed connective tissue disease (MCTD) was found to be associated with intra-articular deposition of carbonated hydroxyapatite crystals. A technetium hydroxymethylene diphosphonate bone scan showed intense uptake in the delayed phase scan of the affected joints. Synovial fluid analysis demonstrated uptake of the radiopharmaceutical drug directly onto the crystals.