Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Positron Emission Tomography01:29

Positron Emission Tomography

6.8K
Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
6.8K
Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

416
Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
416
Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

337
Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
337

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Impact of Atrial and Dual-Chamber Leadless Pacing on Subcutaneous Implantable Cardioverter-Defibrillator Screening Eligibility.

Journal of cardiovascular electrophysiology·2026
Same author

Assessing the imaging calibration factor for quantitative SPECT/CT of actinium-225.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine·2026
Same author

Pilates Method as a complementary activity reduces myofascial stiffness and pain in women with breast cancer undergoing aromatase inhibitor therapy: a randomized controlled trial.

Scientific reports·2026
Same author

Letter to the Editor regarding "Questionable indication for postoperative radiotherapy after surgery for metastases of the major long bones": A cautionary note on methodology and analysis.

Journal of bone oncology·2026
Same author

Micra transcatheter pacing system implantation via the right internal jugular vein: Preliminary results from a Polish multicenter registry.

Kardiologia polska·2026
Same author

Long-term toxicity of tandem radioligand therapy using [<sup>90</sup>Y]Y/[<sup>177</sup>Lu]Lu-DOTA-TATE in neuroendocrine tumors: a polish multicenter experience with 20-year follow-up.

European journal of nuclear medicine and molecular imaging·2026

Related Experiment Video

Updated: Dec 28, 2025

Quantification of Atherosclerotic Plaque Activity and Vascular Inflammation using [18-F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography FDG-PET/CT
10:02

Quantification of Atherosclerotic Plaque Activity and Vascular Inflammation using [18-F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography FDG-PET/CT

Published on: May 2, 2012

18.6K

Sequential delayed [18 F]FDG PET/CT examinations in the pharynx.

Agata Karolina Pietrzak1,2, Andrzej Marszalek3, Joanna Kazmierska4

  • 1Nuclear Medicine Department, Greater Poland Cancer Centre, Garbary 15, 61-866, Poznan, Poland. agata.pietrzakk@gmail.com.

Scientific Reports
|February 21, 2020
PubMed
Summary

Biphasic 2-deoxy-2-[18F]fluoro-D-glucose positron emission tomography/computed tomography (FDG PET/CT) effectively distinguishes benign from malignant pharyngeal lesions. This imaging technique aids in better stratification of normal and abnormal glucose metabolism, improving diagnostic accuracy.

More Related Videos

Functional Imaging of Brown Fat in Mice with 18F-FDG micro-PET/CT
10:53

Functional Imaging of Brown Fat in Mice with 18F-FDG micro-PET/CT

Published on: November 23, 2012

19.7K
Radiotracer Administration for High Temporal Resolution Positron Emission Tomography of the Human Brain: Application to FDG-fPET
09:03

Radiotracer Administration for High Temporal Resolution Positron Emission Tomography of the Human Brain: Application to FDG-fPET

Published on: October 22, 2019

10.7K

Related Experiment Videos

Last Updated: Dec 28, 2025

Quantification of Atherosclerotic Plaque Activity and Vascular Inflammation using [18-F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography FDG-PET/CT
10:02

Quantification of Atherosclerotic Plaque Activity and Vascular Inflammation using [18-F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography FDG-PET/CT

Published on: May 2, 2012

18.6K
Functional Imaging of Brown Fat in Mice with 18F-FDG micro-PET/CT
10:53

Functional Imaging of Brown Fat in Mice with 18F-FDG micro-PET/CT

Published on: November 23, 2012

19.7K
Radiotracer Administration for High Temporal Resolution Positron Emission Tomography of the Human Brain: Application to FDG-fPET
09:03

Radiotracer Administration for High Temporal Resolution Positron Emission Tomography of the Human Brain: Application to FDG-fPET

Published on: October 22, 2019

10.7K

Area of Science:

  • Nuclear Medicine
  • Oncology
  • Radiology

Background:

  • Pharyngeal lesions require accurate differentiation between benign and malignant types for appropriate patient management.
  • Positron emission tomography/computed tomography (PET/CT) using 2-deoxy-2-[18F]fluoro-D-glucose ([18F]FDG) is a key imaging modality for assessing metabolic activity.
  • Evaluating the utility of biphasic [18F]FDG PET/CT in pharyngeal lesion characterization is crucial.

Purpose of the Study:

  • To assess the effectiveness of biphasic [18F]FDG PET/CT in differentiating benign and malignant pharyngeal lesions.
  • To determine optimal metabolic parameters and cut-off values for lesion characterization.
  • To evaluate the role of sequential imaging in assessing glucose metabolism in the pharynx.

Main Methods:

  • 139 patients underwent sequential biphasic [18F]FDG PET/CT scans at 60 and 90 minutes post-injection.
  • Maximal and mean standardized uptake values (SUVmax, SUVmean) and retention index (RI-SUVmax) were analyzed.
  • Receiver operating characteristic (ROC) analysis was employed to identify discriminating metabolic indices.

Main Results:

  • Cut-off SUVmax values of 1.9 and 2.0 at 60 and 90 minutes differentiated normal from abnormal metabolic activity.
  • SUVmax values for benign and malignant lesions were 3.1 and 3.6, respectively.
  • An increase in SUVmax over time of 1.7% suggested abnormality, while RI-SUVmax of 5.7% indicated malignancy.

Conclusions:

  • Biphasic [18F]FDG PET/CT provides valuable information for stratifying normal and abnormal glucose metabolism in the pharynx.
  • The retention index derived from sequential imaging aids in distinguishing malignant from benign pharyngeal lesions.
  • This imaging protocol enhances the diagnostic capability for pharyngeal pathologies.