Screen-printed electrochemical biosensor based on a ternary Co@MoS₂/rGO functionalized electrode for high-performance...

Area of Science:

• Materials Science
• Nanotechnology
• Electrochemistry

Background:

• Development of sensitive and selective glucose sensors is crucial for diabetes management.
• Non-enzymatic glucose detection offers advantages over enzymatic methods by avoiding enzyme-related issues.
• Advanced nanomaterials are key to improving electrochemical sensor performance.

Purpose of the Study:

• To synthesize and characterize a novel ternary nanohybrid of cobalt oxides functionalized MoS2/reduced graphene oxide.
• To develop an ultrasensitive and selective non-enzymatic glucose sensor using this nanohybrid.
• To evaluate the potential of this sensor for point-of-care applications.

Main Methods:

• Facile one-pot hydrothermal synthesis of cobalt oxides/MoS2/reduced graphene oxide.
• Characterization using scanning electron microscopy, transmission electron microscopy, Raman spectroscopy, and X-ray photoelectron spectroscopy.
• Fabrication of a screen-printed electrochemical sensor modified with the nanohybrid and electrochemical testing (cyclic voltammetry, amperometry).

Main Results:

• Successful synthesis of the ternary nanohybrid with defined morphology and crystal structure.
• The modified electrode exhibited superior electro-catalytic activity for glucose oxidation.
• Achieved an ultrasensitive detection limit of 30 nM with excellent selectivity against common interfering species.

Conclusions:

• The cobalt oxides/MoS2/reduced graphene oxide nanohybrid is a promising material for non-enzymatic glucose sensing.
• The developed electrochemical sensor demonstrates high sensitivity and selectivity.
• The integration with screen-printed technology enables potential for portable point-of-care glucose monitoring devices.