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Updated: Dec 28, 2025

Separation and Differential Characterization of Gut Microbial Extracellular Vesicles in Salt-Sensitive Rats under High-Salt Diet Conditions
07:21

Separation and Differential Characterization of Gut Microbial Extracellular Vesicles in Salt-Sensitive Rats under High-Salt Diet Conditions

Published on: June 6, 2025

617

Intestinal Flora Modulates Blood Pressure by Regulating the Synthesis of Intestinal-Derived Corticosterone in High

Xuefang Yan1, Jiajia Jin1, Xinhuan Su2,3

  • 1From the Department of Cardiology, The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences, The State and Shandong Province Joint Key Laboratory of Translational Cardiovascular Medicine, Qilu Hospital of Shandong University, Jinan (X. Yan, J.J., X. Yin, J.G., X.W., S.Z., P.B., Y.Z., Q.Z.).

Circulation Research
|February 21, 2020
PubMed
Summary

High-salt diets can cause hypertension by altering gut bacteria. A specific bacterium, Bacteroides fragilis, and its metabolite, arachidonic acid, help regulate blood pressure by controlling corticosterone levels.

Keywords:
arachidonic acidbacteroidescorticosteronehypertensionmicrobiota

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