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A Murine Model of Group B Streptococcus Vaginal Colonization
Published on: November 16, 2016
Streptococcus agalactiae infections and clinical relevance in adults, Thailand
Wantana Paveenkittiporn1, Ratchadabhorn Ungcharoen2, Anusak Kerdsin2
1National Institute of Health, Department of Medical Sciences, Ministry of Public Health, Thailand.
Abstract:
Streptococcus agalactiae is an important pathogen that causes infections in neonates and adults; infections especially in nonpregnant adults are increasing worldwide. Of 1736 S. agalactiae isolates from individuals throughout Thailand, serotypes III (46.4%) and V (21%) were demonstrated to be the most common serotypes. Human cases (56.5% female and 43.5% male) could be found all year round, with the peak occurring more frequently during the rainy season (May-October). The mortality rate of S. agalactiae infections was 11.6%, and serotype III was the most common serotype involved. Serotype III was strongly significantly (P value <0.001) correlated with meningitis (odds ratio [OR] = 26.72), sepsis (OR = 5.56), and septic arthritis (OR = 22.79). Serotype V was more associated with urinary tract infection than other serotypes. (P value = 0.005; OR = 2.32).
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