A Clinical Study of Basal Cell Carcinoma

Area of Science:

• Dermatology
• Oncology
• Epidemiology

Background:

• Basal cell carcinoma (BCC) is a common non-melanocytic skin cancer with diverse clinical presentations.
• Its development is influenced by genetic, phenotypic, and environmental factors, notably ultraviolet (UV) radiation exposure.

Purpose of the Study:

• To analyze recent clinical trends in basal cell carcinoma (BCC) based on a single institution's experience.
• To identify demographic, clinical, and etiological factors associated with BCC development and recurrence.

Main Methods:

• Retrospective analysis of 422 patients diagnosed with basal cell carcinoma (BCC).
• Data collected included age, gender, skin type, history, lesion characteristics, and recurrence rates.
• Statistical evaluation of collected data.

Main Results:

• Over 80% of BCCs were on sun-exposed skin; nodular BCC (59.2%) was most frequent.
• Nodular and pigmented BCCs common on head/neck; superficial BCC on the trunk.
• Recurrence rate was 9.7%; no cases of metastasis or fatal outcomes were reported.

Conclusions:

• Older age and recreational/occupational UV exposure are key risk factors for BCC.
• Early diagnosis, treatment, and awareness of risk factors are crucial for BCC prevention, especially in susceptible individuals.