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Related Concept Videos

Genetic Screens02:46

Genetic Screens

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Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing  genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which...
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Conservation of Small Populations02:04

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Small population sizes put a species at extreme risk of extinction due to a lack of variation, and a consequent decrease in adaptability. This weakens the chances of survival under pressures such as climate change, competition from other species, or new diseases. Large populations are more likely to survive pressures such as these, as such populations are more likely to harbor individuals that have genetic variants that are adaptive under new stresses. Small populations are much less...
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Conservation of Declining Populations02:07

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Conservation of declining population focuses on ways of detecting, diagnosing, and halting a population decline. The approach uses methods to prevent populations from going extinct.
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Updated: Dec 28, 2025

Silencing the Spark: CRISPR/Cas9 Genome Editing in Weakly Electric Fish
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Transforming Ocean Conservation: Applying the Genetic Rescue Toolkit.

Ben J Novak1, Devaughn Fraser2, Thomas H Maloney1

  • 1Revive & Restore, 1505 Bridgeway #203, Sausalito, CA 94965, USA.

Genes
|February 23, 2020
PubMed
Summary

Marine conservation needs innovative solutions. This study explores using biotechnology and genomics for genetic rescue to protect ocean ecosystems from mounting threats, offering recommendations for responsible deployment.

Keywords:
biodiversitybiotechnologyeDNAgenetic insightgenetic rescuegenomic interventionmarine conservationmarine scienceocean genomics

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Area of Science:

  • Marine Biology
  • Conservation Genetics
  • Biotechnology

Background:

  • Oceans provide critical ecosystem services but face understudied threats.
  • Conventional conservation strategies are insufficient against mounting marine environmental damage.
  • Biotechnology and genomic research offer novel tools for ocean conservation.

Purpose of the Study:

  • To assess opportunities for novel genetic rescue tools in marine conservation.
  • To identify how synthetic biology and genomics can address major marine threats.
  • To evaluate technological and social factors for deploying marine biotechnology.

Main Methods:

  • Conducted the Ocean Genomics Horizon Scan survey.
  • Assessed opportunities for genetic rescue tools in marine conservation.
  • Analyzed technological and social factors for biotechnology deployment.

Main Results:

  • Identified novel approaches from synthetic biology and genomics to alleviate marine threats.
  • Genetic insight can enhance established conservation methods.
  • Genomic intervention may be necessary due to the severity of threats.

Conclusions:

  • Biotechnology and genomic research are crucial for viable ocean ecosystems.
  • Ethical frameworks are necessary for responsible biotechnological interventions.
  • Recommendations are provided for safe and responsible deployment of genetic rescue for marine conservation.