Related Experiment Video
Updated: Aug 19, 2026

The Dimethylnitrosamine Induced Liver Fibrosis Model in the Rat
Published on: June 17, 2016
[Effect of phenozan on nitrosodimethylamine-induced carcinogenesis in rat kidneys]
Abstract:
Fenosan has been studied for its effect on the lipid peroxidation level of mitochondria and microsomes of the rat kidneys in different periods of nitrosodimethylamine-induced carcinogenesis as well as on the incidence of kidney tumour formation. A month after the treatment with the above carcinogen the lipid peroxidation in the rat kidney was activated. An additional injection of fenosan decreased the intensity of the lipid peroxidation and inhibited the tumour development in kidneys. It is supposed that anticarcinogenic action of fenosan is related to the membrane protection from the lesion by the carcinogen.
More Related Videos
07:38A General Method for Detecting Nitrosamide Formation in the In Vitro Metabolism of Nitrosamines by Cytochrome P450s
Published on: September 25, 2017
09:33Formation of Covalent DNA Adducts by Enzymatically Activated Carcinogens and Drugs In Vitro and Their Determination by 32P-postlabeling
Published on: March 20, 2018
Related Concept Videos
2° Amines to N-Nitrosamines: Reaction with NaNO2
Physical Properties of Amines
Mutagenicity and Carcinogenicity