Related Experiment Video
Updated: Dec 28, 2025

A High-Fidelity Porcine Model of Orthotopic Heart Transplantation Following Donation after Circulatory Death
Published on: June 6, 2025
ISHLT consensus statement on donor organ acceptability and management in pediatric heart transplantation
Richard Kirk1, Anne I Dipchand2, Ryan R Davies3
1Division of Pediatric Cardiology, University of Texas Southwestern Medical Center, Children's Medical Center, Dallas, Texas.
Insights
Many donated pediatric hearts are discarded, increasing waitlist mortality. This statement provides recommendations to reduce organ discard and improve outcomes for children awaiting heart transplants.
Area of Science:
- Cardiology
- Transplantation Medicine
- Pediatric Health
Background:
- Pediatric heart transplantation faces a persistent donor organ shortage, leading to significant waitlist mortality.
- A substantial proportion, approximately 40%, of donated hearts are discarded, representing a loss of viable organs.
- This situation highlights a critical gap between the need for pediatric heart transplants and the availability of suitable organs.
Abstract:
The number of potential pediatric heart transplant recipients continues to exceed the number of donors, and consequently the waitlist mortality remains significant. Despite this, around 40% of all donated organs are not used and are discarded. This document (62 authors from 53 institutions in 17 countries) evaluates factors responsible for discarding donor hearts and makes recommendations regarding donor heart acceptance. The aim of this statement is to ensure that no usable donor heart is discarded, waitlist mortality is reduced, and post-transplant survival is not adversely impacted.
Related Concept Videos
Kidney Transplant I: Introduction
Tissue Transplantation
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
Kidney Transplant II: Surgical Procedure

