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A Canine Model for Lymphangiography and Thoracic Duct Access
Kun Yung Kim1, Jung Hoon Park2, Jiaywei Tsauo3
1Department of Radiology and Research Institute of Clinical Medicine of Chonbuk National University-Biomedical Research Institute of Chonbuk National University Hospital, Jeonju, Korea.
Korean Journal of Radiology
|February 25, 2020
Summary
A canine model is suitable for intranodal lymphangiography and thoracic duct access. Lymphatic interventions in dogs can utilize standard clinical instruments, demonstrating technical feasibility for future research.
Area of Science:
- Veterinary Medicine
- Interventional Radiology
- Lymphatic System Imaging
Background:
- Intranodal lymphangiography and thoracic duct (TD) access are crucial for lymphatic interventions.
- Establishing a reliable animal model is essential for refining these techniques.
Purpose of the Study:
- To assess the technical feasibility of performing intranodal lymphangiography and thoracic duct access in a canine model.
- To determine if standard clinical instruments are applicable in this animal model.
Main Methods:
- Five mongrel dogs underwent ultrasonography-guided intranodal injection of Lipiodol.
- Direct puncture and cannulation of the cisterna chyli (CC) were performed.
- Transvenous retrograde catheterization of the TD was achieved using a snare kit.
Main Results:
- Ultrasonography-guided lymphangiography was successful in all dogs.
- Cisterna chyli puncture and thoracic duct access were successful in all dogs.
- Lipiodol extravasation occurred in 60% of dogs, necessitating additional interventions.
Conclusions:
- A canine model is technically feasible for intranodal lymphangiography and thoracic duct access.
- Standard clinical instruments are applicable for lymphatic interventions in canines.
- This model provides a platform for further research into lymphatic interventions.
